KEGG   Bos taurus (cow): 281601
Entry
281601            CDS       T01008                                 
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase type 1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
bta  Bos taurus (cow)
Pathway
bta00230  Purine metabolism
bta01100  Metabolic pathways
bta01522  Endocrine resistance
bta04015  Rap1 signaling pathway
bta04020  Calcium signaling pathway
bta04022  cGMP-PKG signaling pathway
bta04024  cAMP signaling pathway
bta04062  Chemokine signaling pathway
bta04072  Phospholipase D signaling pathway
bta04114  Oocyte meiosis
bta04211  Longevity regulating pathway
bta04213  Longevity regulating pathway - multiple species
bta04261  Adrenergic signaling in cardiomyocytes
bta04270  Vascular smooth muscle contraction
bta04371  Apelin signaling pathway
bta04540  Gap junction
bta04611  Platelet activation
bta04713  Circadian entrainment
bta04714  Thermogenesis
bta04720  Long-term potentiation
bta04723  Retrograde endocannabinoid signaling
bta04724  Glutamatergic synapse
bta04725  Cholinergic synapse
bta04727  GABAergic synapse
bta04750  Inflammatory mediator regulation of TRP channels
bta04911  Insulin secretion
bta04912  GnRH signaling pathway
bta04913  Ovarian steroidogenesis
bta04914  Progesterone-mediated oocyte maturation
bta04915  Estrogen signaling pathway
bta04916  Melanogenesis
bta04918  Thyroid hormone synthesis
bta04921  Oxytocin signaling pathway
bta04923  Regulation of lipolysis in adipocytes
bta04925  Aldosterone synthesis and secretion
bta04926  Relaxin signaling pathway
bta04927  Cortisol synthesis and secretion
bta04928  Parathyroid hormone synthesis, secretion and action
bta04934  Cushing syndrome
bta04935  Growth hormone synthesis, secretion and action
bta04970  Salivary secretion
bta04971  Gastric acid secretion
bta04972  Pancreatic secretion
bta04976  Bile secretion
bta05032  Morphine addiction
bta05142  Chagas disease
bta05146  Amoebiasis
bta05163  Human cytomegalovirus infection
bta05166  Human T-cell leukemia virus 1 infection
bta05200  Pathways in cancer
bta05207  Chemical carcinogenesis - receptor activation
bta05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    281601 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    281601 (ADCY1)
   04371 Apelin signaling pathway
    281601 (ADCY1)
   04020 Calcium signaling pathway
    281601 (ADCY1)
   04072 Phospholipase D signaling pathway
    281601 (ADCY1)
   04024 cAMP signaling pathway
    281601 (ADCY1)
   04022 cGMP-PKG signaling pathway
    281601 (ADCY1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    281601 (ADCY1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    281601 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    281601 (ADCY1)
   04062 Chemokine signaling pathway
    281601 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    281601 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    281601 (ADCY1)
   04912 GnRH signaling pathway
    281601 (ADCY1)
   04913 Ovarian steroidogenesis
    281601 (ADCY1)
   04915 Estrogen signaling pathway
    281601 (ADCY1)
   04914 Progesterone-mediated oocyte maturation
    281601 (ADCY1)
   04921 Oxytocin signaling pathway
    281601 (ADCY1)
   04926 Relaxin signaling pathway
    281601 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    281601 (ADCY1)
   04918 Thyroid hormone synthesis
    281601 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    281601 (ADCY1)
   04916 Melanogenesis
    281601 (ADCY1)
   04925 Aldosterone synthesis and secretion
    281601 (ADCY1)
   04927 Cortisol synthesis and secretion
    281601 (ADCY1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    281601 (ADCY1)
   04270 Vascular smooth muscle contraction
    281601 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    281601 (ADCY1)
   04971 Gastric acid secretion
    281601 (ADCY1)
   04972 Pancreatic secretion
    281601 (ADCY1)
   04976 Bile secretion
    281601 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    281601 (ADCY1)
   04727 GABAergic synapse
    281601 (ADCY1)
   04725 Cholinergic synapse
    281601 (ADCY1)
   04720 Long-term potentiation
    281601 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    281601 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    281601 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    281601 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    281601 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    281601 (ADCY1)
   04714 Thermogenesis
    281601 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    281601 (ADCY1)
   05207 Chemical carcinogenesis - receptor activation
    281601 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    281601 (ADCY1)
   05163 Human cytomegalovirus infection
    281601 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    281601 (ADCY1)
   05142 Chagas disease
    281601 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    281601 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    281601 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    281601 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    281601 (ADCY1)
Enzymes [BR:bta01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     281601 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom HNOBA DUF6688
Other DBs
NCBI-GeneID: 281601
NCBI-ProteinID: NP_776654
BGD-bta: BT10524
Ensembl: ENSBTAG00000009520
VGNC: 25642
UniProt: P19754
Position
4:complement(76174089..76273756)
AA seq 1134 aa
MAGAPRGRGGGGGGGGAGESGGAERAAGPGGRRGLRACDEEFACPELEALFRGYTLRLEQ
AATLKALAVLSLLAGALALAELLGAPGPAPGLAKGSHPVHCVLFLALLVVTNVRSLQVPQ
LQQVGQLALLFSLTFALLCCPFALGGPAGAHAGAAAVPATADQGVWQLLLVTFVSYALLP
VRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLGVNVYGIFVRILAERA
QRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQR
HDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVS
GLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDV
WSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVP
SHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRA
LRTASEKLRNRSSFSTNVVQTTPGTRVNRYIGRLLEARQMELEMADLNFFTLKYKQAERE
RKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFCICFLVACVLYLHIT
RVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWSWSSSPNGSLVVLSSGGRDPV
LPVPPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLAVLTTSYILVLELSGYTKAMGA
GAISGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRIL
FNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLL
NEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIE
MFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGR
IQVTEEVHRLLRRGSYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQTRSLNSERKMYPF
GRAGLQTRLAAGHPPVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGASGKEA
NT seq 3405 nt   +upstreamnt  +downstreamnt
atggcgggggcgccgcgcggccgaggcggcggcggaggcggaggcggcgcgggcgagtct
gggggcgccgagcgggcggcggggccgggcggccggcgcgggctgcgggcgtgcgatgag
gagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcag
gcggcgacgctgaaggcgctggccgtgctcagcctgctggcgggcgcgctggccctggcc
gagctgctgggcgcgccggggcccgcgcccggcctggctaagggctcgcaccccgtgcac
tgcgtgctcttcctggcgctgctcgtggtcaccaacgtccgctcgctgcaggtgccccag
ctgcagcaggtcggccagctcgcgctgctcttcagcctcaccttcgctctgctgtgctgt
cccttcgcgctcggcggccccgccggtgcccacgccggggcggcagcggtgccggcgaca
gccgatcagggagtctggcagctccttttggtcaccttcgtgtcctatgccctgctgccc
gtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacttgctggtc
acggctacgttggtccccgccaagcgcccacgtctctggagaacgctgggtgccaacgct
ctgctcttcctcggtgtgaacgtgtatggcatcttcgtgaggatcctggctgagcgcgcc
cagaggaaggccttcctgcaggcccggaactgcattgaggaccggctgaggctggaggat
gagaatgagaagcaggagcggctgctcatgagcctcctgcctcggaatgttgccatggag
atgaaggaggacttcctgaagccccctgagaggattttccacaagatttacatccagcgg
catgacaacgtgagcatcctctttgcagacatcgtgggcttcacaggcttggcgtcacag
tgcacggcccaggagctggtgaaactcctcaatgagctcttcgggaagtttgacgagctg
gccacagagaaccactgccgccgcatcaagatcctgggagattgctactactgcgtgtct
ggcctcactcagcccaagactgaccacgcccactgctgtgtggagatgggcctggacatg
atcgacaccatcacgtccgtggctgaggccactgaggtggacttgaacatgcgtgtgggg
ctgcacaccggcagggtcctctgcggggtcctgggcctgcgtaagtggcagtatgatgtg
tggtccaacgacgtgaccctggccaacgtcatggaggctgccggcctgcctgggaaggtt
cacatcacaaagaccaccctggcgtgcctgaatggtgactatgaggtggagccgggacac
ggacacgagaggaacagttttctgaaaactcataacattgagaccttttttattgtgccc
tcgcatcggcgaaagatatttccagggctgattctctcagacataaaaccggccaagagg
atgaagttcaagaccgtgtgctacctgctggtgcagctcatgcactgccggaagatgttc
aaggccgagatccctttctccaacgtcatgacctgtgaggatgacgacaagcggagggca
ctgagaacagcctcggaaaaactcagaaaccgctcgtctttctctacaaacgttgtccaa
accacccccggcacacgtgtcaacaggtacatcggccgcctcctggaagcccgccagatg
gagctggagatggcagacctgaacttcttcaccctgaagtacaagcaagctgagcgagag
cgaaagtaccaccagcttcaggacgagtatttcaccagcgccgtggttctggctctcatt
ctggccgccttattcggccttgtctaccttctaataatcccacagagtgtggctgtcctg
ctcctgctggtgttctgcatctgcttcctggtggcctgtgtcctgtacctacacatcacc
cgggtccagtgttttccagggtgcctgaccatccagatccgcaccgtcttgtgcatcttc
atcgtggtcttaatctactctgtggcccaaggctgtgtggtgggctgcctgccttggtcc
tggagctccagtcccaacgggtccctggtggtcctgtcttctgggggccgggacccagtg
ctgcctgtcccgccctgcgagtctgcgccccatgccctgctgtgcggcctcgtgggcacc
ctcccgctggccatattcctgcgggtctcctccttgccaaaaatgatcctgctcgccgtg
ctcaccacctcctacatcctcgtcctggagctcagcgggtacacgaaggccatgggggcc
ggtgccatctcagggcgcagcttcgagccgatcatggccatcctgctattctcgtgcacg
ctggccctgcacgcccggcaggtggatgtcaagctgcggctggactacctctgggcggcc
caggcagaggaggagcgggatgacatggagaaagtgaagctggacaacaagaggattctc
ttcaacctcctgccagcccacgttgcccagcacttcctaatgtccaaccctcgcaacatg
gacctgtattaccagtcatactcgcaggtgggggtcatgtttgcatccatccccaacttc
aatgacttctacatcgagctggatggcaacaacatgggggtggaatgtctacgccttctg
aatgagatcatcgctgactttgatgagctcatggacaaagacttttacaaggacctagag
aagatcaagaccattgggagcacgtacatggctgctgtggggctggcgcccactgctggg
accaaggctaagaagtgcatctcctcccacctcagcacgttggcagattttgccatcgag
atgtttgatgtcctggatgagatcaactaccagtcttataacgactttgtgctccgtgtt
ggcatcaatgttggccccgtggtggctggagtgatcggggctcgcaggccgcagtatgac
atttgggggaacacggtcaatgtggccagtcggatggacagtaccggcgtccagggcagg
atccaggtcacagaggaagttcaccggctgctgcggcggggttcctaccgcttcgtgtgc
cgaggcaaagtcagtgtcaagggcaagggtgagatgctgacatacttcctggaaggcagg
accgatggaaatggctcccaaaccaggtccctgaactcagagcggaaaatgtatcctttc
ggaagagctggcctccagaccagactggctgcgggtcaccccccggtacctcctgcagcc
ggcctcccagttggagctgggccaggggctctgcagggctcggggcttgccccaggcccc
ccaggccaacacctgccccctggagcctctgggaaggaggcttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (52)   
   KEGG PATHWAY (52)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (5)   
   Pfam (5)   
All databases (90)   

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